The developed vaccine has shown impressive results in experimental mice: according to previous studies, it is capable of not only reducing tumor sizes but also completely eliminating them. New research has confirmed its preventive action.
During the experiment, the vaccine was administered to mice along with tumor peptides, and three weeks later, the rodents were implanted with cancer cells that cause aggressive tumors. As a result, the vaccine was able to prevent the development of pancreatic cancer, melanoma, and triple-negative breast cancer in 88% of cases. Additionally, 80% of the studied mice survived throughout the observation period, which lasted 250 days, while the control group mice, which received traditional vaccines, lived for less than 35 days.
It should also be noted that the vaccine provided protection against metastasis in the event of tumor formation. "This is a significant advantage, as metastases remain the main cause of mortality in cancer," researchers emphasize.
The authors of the study are confident that their vaccine will be effective against various types of tumors. Currently, the trials are at the preclinical stage.
Recently, other scientists from the USA presented an mRNA vaccine that also activates the immune system in the fight against tumors but uses a different mechanism of action.
