Within the framework of the study, information from the medical records of 130 patients was analyzed using statistical methods such as the Mann-Whitney U test, χ², and the calculation of relative odds, conducted in the StatTech v.4.8.7 program.
The results of the study showed that almost half of the examined patients (48.5%) suffer from polypharmacy. This condition was significantly associated with advanced stages of cancer (54% compared to 20.9%), the prescription of palliative treatment (76.2% versus 46.3%), and frequent therapy interruptions (65.1% versus 20.9%; odds ratio=7). Such patients exhibit more pronounced comorbidity, while echocardiographic examinations are conducted less frequently (65.1% versus 80.6%).
The authors of the study note that polypharmacy can serve as an indicator of a complex clinical condition. This necessitates the development of optimized approaches to patient management, enhanced cardiac monitoring, and mandatory echocardiography to improve the safety of therapeutic interventions.
The findings of the study confirm the need for a comprehensive approach in the therapy of cancer patients with cardiovascular diseases and emphasize the importance of integrating cardiological monitoring into standard clinical protocols.
